Proposed roles include maintenance of tightjunction barriers, signaling and junction remodeling.
2
PKC-ζ inhibition also attenuated AGE-induced decrease of tightjunction proteins in HRMECs.
3
Results showed reversible recovery on the expression of tightjunction markers.
4
Proteins responsible for tightjunction integrity are upregulated in hypertonic states.
5
The tightjunction of epithelial cells excludes macromolecules but allows permeation of ions.
1
Microvillis and zonulaoccludens were observed on the surface of the differentiated cells under an electron microscope.
2
Most gap junctions between neurons in mammalian retina contain abundant connexin36, often in association with the scaffolding protein zonulaoccludens-1.
3
The expression and membrane localization of the tight junction proteins zonulaoccludens-1 and occludin were decreased in alveolar epithelial cells from HIV-1 transgenic rats.
Uso de tight junctions en inglés
1
Sequestration of CAR in tightjunctions may limit virus infection across epithelial surfaces.
2
They create tightjunctions with mouse hepatocytes, with no evidence of cell fusion.
3
This isoform of TOCA-1 recruits the actin nucleation-promoting factor N-WASP to tightjunctions.
4
JAM-A localizes to tightjunctions and contributes to paracellular permeability in polarized epithelia.
5
Adherens junctions are calcium dependent; recent evidence suggests that calcium also affects tightjunctions.
6
Virus entry into polarized epithelium required disruption of tightjunctions.
7
Thus, this was the first description of the existence of tightjunctions in the epidermis.
8
This study explores the expression and distribution of tightjunctions and their regulation during pregnancy.
9
The structural integrity of intestinal mucosa and tightjunctions were observed by transmission electron microscopy.
10
Obvious damage was observed in the mucosa, but the tightjunctions between epithelial cells remained intact.
11
He described the cell-to-cell adhesion structures that blocked the movement of lanthanum as 'truly tightjunctions'.
12
We also found that MMP9 maintains an efficient barrier function and the integrity of tightjunctions.
13
These cells formed bile canaliculi sealed by tightjunctions and were comparably polarized as cultured hepatocytes.
14
CAR is involved in the formation of epithelial tightjunctions and promotes tumor growth in some cancers.
15
These endothelial cells maintain their barrier characteristics via cell-cell contacts made up of adherens and tightjunctions.
16
Thanks to the discovery of claudin, the existence of tightjunctions between epidermal keratinocytes was finally confirmed.